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KMID : 1038820150180010010
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Pediatric Gastroenterology, Hepatology & Nutrition
2015 Volume.18 No. 1 p.10 ~ p.16
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Changing Prevalence of Helicobacter pylori Infections in Korean Children with Recurrent Abdominal Pain
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Jang Kyung-Mi
Choe Byung-Ho
Choe Jae-Young
Hong Suk-Jin
Park Hyo-Jung
Chu Mi-Ae
Cho Seung-Man
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Abstract
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Purpose: The aim of this study is to investigate the changing prevalence rate of Helicobacter pylori infection in children,of different age groups, with recurrent abdominal pain over a 10-year period.
Methods: Children with recurrent abdominal pain who visited the pediatric outpatient clinic at university hospital werescreened for H. pylori. Children were divided into 3 age categories of 4-5, 6-11, and 12-16 years. To study the changesin the annual prevalence rates of H. pylori infection, the study period was divided into 3 time periods: 2004-2007,2008-2010, and 2011-2014. Urea breath test was performed for all children aged 4-16 years, with a cut-off valueof 4.0‰ for children aged ≥6 years and 7‰ for children aged ＜6 years.
Results: A total of 2,530 children (1,191 boys) with a mean age of 10.0±3.0 years (range, 4.0-16.9 years) were includedin the study. The total prevalence of H. pylori infection was 7.4% (187/2,530). The prevalence rate of H. pylori infectionin children with recurrent abdominal pain was 8.0% (70/873) in 2004-2007, 7.7% (51/666) in 2008-2010, and 6.7%(66/991) in the 2011-2014. Nevertheless, a significant difference was observed in the prevalence rate between children＜12 years old and ≥12 years of age (p=0.018).
Conclusion: The prevalence of H. pylori infection in Korean children with recurrent abdominal pain was 7.4%, showingno significant decrease in the last 11 years; however, the prevalence rate in children ＜12 years old was significantlylower than that in those ≥12 years old.
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KEYWORD
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Helicobacter, Functional gastrointestinal disorder, Breath test, Endoscopy, Child
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